Selasa, 13 September 2011

ScienceDaily Health Headlines -- for Tuesday, September 13, 2011

ScienceDaily Health Headlines

for Tuesday, September 13, 2011

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Tinnitus discovery could lead to new ways to stop the ringing: Retraining the brain could reanimate areas that have lost input from the ear (September 13, 2011) -- People with tinnitus -- a constant ringing or buzzing in the ears -- can take heart from a new study by neuroscientists that points to several new strategies for alleviating the problem. In experiments on rats, researchers have shown that tinnitus results from decreased inhibition in the auditory cortex. Thus, training that boosts inhibition or drugs that increase the levels of inhibitory neurotransmitter may alleviate the symptoms. ... > full story

Study evaluates intranasal insulin therapy for adults with mild cognitive impairment or Alzheimer’s (September 13, 2011) -- Intranasal insulin therapy appears to provide some benefit for cognitive function in patients with amnestic mild cognitive impairment and Alzheimer disease, according to a new study. ... > full story

Association found between long-term use of nonaspirin anti-inflammatory drugs and renal cell cancer (September 13, 2011) -- Long-term use of nonaspirin anti-inflammatory drugs (NSAIDs) is associated with an increased risk of renal cell cancer (RCC), according to a report in the Sept. issue of Archives of Internal Medicine, one of the JAMA/Archives journals. ... > full story

U.S. public may not be aware of important uncertainties about drug benefits and harms (September 13, 2011) -- Many U.S. adults believe that only extremely effective drugs without serious adverse effects are approved, but providing explanations to patients highlighting uncertainties about drug benefits may affect their choices, according to a new study. ... > full story

Recycling fat might help worms live longer (September 13, 2011) -- Scientists found that two cellular processes -- lipid metabolism and autophagy -- work together to influence lifespan in C. elegans worms. Autophagy, a mechanism cells use to recycle their own contents, has been implicated in many human diseases, including cancer. This study provides a more detailed understanding of the roles autophagy and lipid metabolism play in aging. ... > full story

Gene responsible for three forms of childhood neurodegenerative diseases found (September 13, 2011) -- An international team has identified the mutated gene responsible for three forms of leukodystrophies, a group of childhood-onset neurodegenerative disorders. ... > full story

First German genome decoded; Researchers analyze two chromosome sets in the human genome separately for the first time (September 13, 2011) -- Errors in the copying and reading of genes can have very serious consequences. Fortunately human genetic material is available in duplicate as everyone inherits a complete genome from both their mother and father. However, the two genomes are different: researchers refer to the different variants of the gene sequence on the individual chromosomes as "haplotypes" and the complete analysis of the genome requires detailed knowledge of both haplotypes. Scientists have now comprehensively decoded both sets of chromosomes from a human genome separately for the first time. This step is essential for gaining a deeper understanding of human biology, the analysis of disease risks and, accordingly, the development of new and more individualised strategies for the prevention and treatment of diseases. The genome fully decoded is also the first completely sequenced genome of a German individual. ... > full story

Confronting meaninglessness (September 13, 2011) -- You've just finished an amazing dinner at your favorite restaurant and you are ready to put on your comfy pajamas and slip into sweet slumber. You arrive at your doorstep and find the front door ajar. Your heart beats wildly in your chest and you peer in, only to discover that your house has been ransacked. Researchers explore the possibility that different threat-reduction approaches can be adaptive in different situations. ... > full story

Novel drug combination offers therapeutic promise for hard-to-treat cancers (September 12, 2011) -- Researchers have identified a new combination of targeted therapies that, together, may treat two aggressive tumor types that until now have not had effective treatments. ... > full story

X-ray protein probe leads to potential anticancer tactic (September 12, 2011) -- Researchers have identified a new type of potential anticancer drug. The compound, named FOBISIN, targets 14-3-3 proteins, important for the runaway growth of cancer cells. The researchers were using X-rays to see how FOBISIN fits into the clamp-shaped 14-3-3 protein structure. Unexpectedly, the X-rays induced the compound to be permanently bonded to the protein. ... > full story

Study finds no link between intracerebral hemorrhage and statin use among patients with prior stroke (September 12, 2011) -- Among patients who have had an ischemic stroke, use of cholesterol-lowering statin medications is not associated with subsequent intracerebral hemorrhage (bleeding in the brain), according to a new study. ... > full story

Pain relievers could calm dementia patients, study suggests (September 12, 2011) -- Many dementia patients are being treated with antipsychotic medications, but a new study by researchers in Norway and the UK shows that simple pain relievers may be a better alternative. ... > full story

Link between high cholesterol and Alzheimer's disease revealed in new study (September 12, 2011) -- People with high cholesterol may have a higher risk of developing Alzheimer's disease, according to a new study. ... > full story

Blacks develop high blood pressure one year faster than whites, study finds (September 12, 2011) -- Blacks at risk of having high blood pressure develop the condition one year before whites and have a 35 percent greater chance of progressing from pre-hypertension to high blood pressure, according to a new study. More aggressive treatment of pre-hypertension could narrow the gap in hypertension rates between blacks and whites. ... > full story

Raising a child doesn't necessarily take a village, study of African villages suggests (September 12, 2011) -- It doesn't take a village to raise a child after all, according to recent research of African villages in Mali. ... > full story

'Trojan Horse' particle sneaks chemotherapy in to kill ovarian cancer cells (September 12, 2011) -- A common chemotherapy drug has been successfully delivered to cancer cells inside tiny microparticles using a method inspired by our knowledge of how the human immune system works. The drug, delivered in this way, reduced ovarian cancer tumors in an animal model by 65 times more than using the standard method. This approach is now being developed for clinical use. ... > full story

Breast cancer patients with BRCA gene diagnosed almost eight years earlier than generation before (September 12, 2011) -- Women with a deleterious gene mutation are diagnosed with breast cancer almost eight years earlier than relatives of the previous generation who also had the disease and/or ovarian cancer, according to new research. ... > full story

New method could help prevent osteoarthritis (September 12, 2011) -- A new method is set to help doctors diagnose osteoarthritis at such an early stage that it will be possible to delay the progression of the disease by many years, or maybe even stop it entirely. ... > full story

Physicist detects movement of macromolecules engineered into our food (September 12, 2011) -- Toxin proteins are genetically engineered into our food because they kill insects by perforating body cell walls, and now researchers studying membrane proteins have detected the molecular mechanism involved. ... > full story

Social contacts, self-confidence crucial to successful recovery through Alcoholics Anonymous, study finds (September 12, 2011) -- Among the many ways that participation in Alcoholics Anonymous helps its members stay sober, two appear to be most important -- spending more time with individuals who support efforts towards sobriety and increased confidence in the ability to maintain abstinence in social situations. Researchers now report the first study to examine the relative importance of behavior changes associated with participation in AA on successful recovery. ... > full story

Exposure to 'white' light LEDs appears to suppress body's production of melatonin more than certain other lights, research suggests (September 12, 2011) -- Exposure to the light of 'white' LED bulbs appears to suppress melatonin five times more than exposure to the light of high pressure sodium bulbs that give off an orange-yellow light, according to new research. ... > full story

Hyperventilation may trigger febrile seizures in children; Controlling acid-base status could lead to novel treatment strategies (September 12, 2011) -- New research shows that febrile seizures in children may be linked to respiratory alkalosis, indicated by elevated blood pH and low carbon dioxide levels caused by hyperventilation, and independent of the underlying infection severity. Febrile seizures were not observed in susceptible children with fevers brought on by gastroenteritis, suggesting that low blood pH levels (acidosis) may have a protective effect. ... > full story

Fast-paced, fantastical television shows may compromise learning, behavior of young children (September 12, 2011) -- Young children who watch fast-paced, fantastical television shows may become handicapped in their readiness for learning, according to a new study. ... > full story

Have we met before? Direct connections found between areas of brain responsible for voice and face recognition (September 12, 2011) -- Researchers have discovered direct connections between the areas of the brain responsible for voice and face recognition. Recent findings indicate that voice and face recognition are much more closely related than previously thought. ... > full story

Scientists successfully expand bone marrow-derived stem cells in culture (September 12, 2011) -- All stem cells -- regardless of their source -- share the remarkable capability to replenish themselves by undergoing self-renewal. Yet, so far, efforts to grow and expand scarce hematopoietic (or blood-forming) stem cells in culture for therapeutic applications have been met with limited success. Now, researchers have teased apart the molecular mechanisms enabling stem cell renewal in hematopoietic stem cells isolated from mice and successfully applied their insight to expand cultured hematopoietic stem cells a hundredfold. ... > full story

New complex offers potentially safer alternative for gene therapy delivery (September 12, 2011) -- Spontaneous ordering of DNA fragments in a special matrix holds the key to creating non-toxic gene therapy delivery vectors, according to a new study. ... > full story

99-cent pricing may not be worth the penny, says expert (September 12, 2011) -- Just-below pricing, or 99-cent endings, is a common marketing tool used to attract customers looking to get bang for their buck. But an expert says that, in some cases, a penny saved doesn't always translate into a penny earned for retailers. ... > full story

Genome-wide hunts reveal new regulators of blood pressure; Genetic variants linked to increased risk of hypertension, stroke and other cardiovascular diseases (September 12, 2011) -- A study involving more than 200,000 people worldwide has identified 29 DNA sequence variations in locations across the human genome that influence blood pressure. These genes, whose sequence changes are associated with alterations in blood pressure and are linked to heart disease and stroke, were found with the help of decades' worth of population data that were pooled and analyzed by a large international consortium. ... > full story

Scientists offer way to address 'age-old' questions (September 12, 2011) -- Scientists have devised a method to measure the impact of age on the growth rates of cellular populations, a development that offers new ways to understand and model the growth of bacteria, and could provide new insights into how genetic factors affect their life cycle. ... > full story

School support for ADHD children may be missing the mark: Inattention, not hyperactivity, is associated with educational failure (September 12, 2011) -- New research shows that inattention, rather than hyperactivity, is the most important indicator when it comes to finishing a high school education. ... > full story

Research points to potential therapy for tumor-associated epilepsy (September 12, 2011) -- Brain tumors called gliomas are often associated with seizures, but why the seizures occur and how to effectively treat them have been elusive. A research team has found that human gliomas implanted in mice release excess levels of the brain chemical glutamate, overstimulating neurons near the tumor and triggering seizures. Sulfasalazine, a drug on the market for treating certain inflammatory disorders, reduced seizures in the mice. ... > full story

Fragile X-associated tremor/ataxia syndrome may be linked to dysregulated neuronal RNA transport, study suggests (September 12, 2011) -- A new study suggests that cellular dysregulation associated with certain neurodegenerative disorders may result from molecular competition in neuronal RNA transport pathways. ... > full story

Withdrawing life support for traumatic brain injuries needs cautious approach, study finds (September 12, 2011) -- Death following severe traumatic brain injury is associated with a highly variable incidence of withdrawal of life support at the end of life, finds a new study. Rates of withdrawal of life support vary between hospitals, and caution should be used in making this decision, the study states. ... > full story

Neuroscientists find famous optical illusion surprisingly potent (September 12, 2011) -- Scientists have figured out the brain mechanism that makes an optical illusion first reported thousands of years ago by Aristotle work. The illusion, known as "motion aftereffect" in scientific circles, causes us to see movement where none exists. ... > full story

Critical similarity found between two types of do-it-all stem cells (September 12, 2011) -- Scientists report the first full measurement of the proteins made by both types of stem cells. In a study that looked at four embryonic stem cells and four IPS cells, the proteins turned out to be 99 percent similar, say researchers. ... > full story

Inexpensive infection control measures could save thousands of lives, billions of dollars (September 12, 2011) -- At any given time, one of every 20 hospital patients has a hospital-acquired infection, according to the U.S. Department of Health and Human Services. This leads to an estimated 99,000 deaths in the U.S. each year and up to billion in preventable health care costs. Now a new study finds that adopting an inexpensive set of infection control measures could potentially save many thousands of lives and billions of dollars. ... > full story

Awareness of ethnicity-based stigma found to start early (September 12, 2011) -- A new study examines more than 450 second and fourth graders in New York City with ethnic-minority and -majority backgrounds. Researchers asked children questions pertaining to their anxiety toward school and feelings of belonging in school. Compared to ethnic-majority peers, ethnic-minority children reported more awareness of stigma and higher academic anxiety. Ethnic-minority children in this study also reported high interest in school in the face of stigma. ... > full story

Researcher launches teen contraceptive website (September 12, 2011) -- In an attempt to provide a reliable and trustworthy source for reproductive health information for teenagers, one physician-researcher has launched the website Ask A Doc RI. ... > full story

Innovating to improve women and children's health (September 12, 2011) -- For less than 0, poor, pregnant women in India can now give birth in a private hospital focusing on low-income families, with comparable quality to expensive, private ones. This is an alternative to overcrowded, poorly staffed government-funded hospitals. Lifespring is a rapidly growing chain of hospitals in India that provides maternity and delivery care. For one low price, as little as , it provides complete delivery services. This is one-third to one-half of the fees charged at other hospitals. ... > full story

Lung cancer signatures in blood samples may aid in early detection (September 12, 2011) -- Lung cancer is one of the most common and deadly types of cancer. Mouse models of lung cancer recapitulate many features of the human disease and have provided new insight about cancer development, progression and treatment. Now, a new study identifies protein signatures in mouse blood samples that reflect lung cancer biology in humans. ... > full story

One in five Canadians has metabolic syndrome (September 12, 2011) -- Approximately one in five Canadians has metabolic syndrome -- a combination of risk factors for diabetes and heart disease -- according to a new study. ... > full story

Common gene variant associated with aortic dissection: Study reveals risk factor that doubles chance of developing silent killer (September 11, 2011) -- Richard Holbrooke, John Ritter, Lucille Ball, Jonathan Larson and Great Britain's King George II were all taken by the same silent killer: an acute aortic dissection. Now, scientists have found an association with a common genetic variant in the population that predisposes people to acute dissections and can approximately double a person's chances of having the disease. ... > full story

Researchers team with glowing cats against AIDS, other diseases; New technique gives cats protection genes (September 11, 2011) -- Researchers have developed a genome-based immunization strategy to fight feline AIDS and illuminate ways to combat human HIV/AIDS and other diseases. ... > full story

Improvements are needed for accuracy in gene-by-environment interaction studies, experts say (September 11, 2011) -- A new study concludes that genetic research drawing correlations between specific genes, environmental variables and the combined impact they have on the development of some psychiatric illnesses needs additional scrutiny and replication before being accepted as true. ... > full story

Peer pressure? It's hardwired into our brains, study finds (September 11, 2011) -- A new study explains why people take stupid chances when all of their friends are watching that they would never take by themselves. According to the study, the human brain places more value on winning in a social setting than it does on winning when you're alone. ... > full story

New target for treating symptoms of Parkinson's disease (September 11, 2011) -- A scientist has identified how the lack of a brain chemical known as dopamine can rewire the interaction between two groups of brain cells and lead to symptoms of Parkinson's disease. This discovery offers new hope for treating those suffering from this devastating neurodegenerative disease. ... > full story

Chemotherapy is as effective before breast cancer surgery as after, study suggests (September 11, 2011) -- Whether chemotherapy is given before or after breast-conserving therapy does not have an impact on long-term local-regional outcomes, suggesting treatment success is due more to biologic factors than chemotherapy timing, according to a new study. ... > full story

A more progressive tax system makes people happier, 54-nation study finds (September 11, 2011) -- The way some people talk, you'd think that a flat tax system -- in which everyone pays at the same rate regardless of income -- would make citizens feel better than more progressive taxation, where wealthier people are taxed at higher rates. Indeed, the United States has been diminishing progressivity of its tax structure for decades. But a new study comparing 54 nations found that flattening the tax risks flattening social wellbeing as well. ... > full story


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